How Blood Saves Life:
350-450 ml of Whole Blood is collected from Healthy Blood Donor & it’s separated into various components like: Packed R.B, Cs , Plasma ( & Stored as Fresh Frozen Plasma ), Platelets & Cryoprecipitate.
Each of the components are used to save Life in different needs.
Packed R.B.C:
In Severe anemia (Hemoglobin % is Low) : In a Patient generally One Unit of Blood Transfusion Increases Hb % by 1 gm % in a person with 60 Kg Weight( with No active Bleeding )
In Thalassemia (Genetic defect Alfa &/or Beta Chains): RBCs have short life span so for patients’ survival and healthy life continuous repeated Blood Transfusions are needed.
In Sickle cell anemia: Genetic Defect: RBCs have Fetal Hemoglobin & form Soccer shape at high altitude, Due to RBC shape is destroyed in spleen rapidly causing anemia.
During Operative Procedures There is Blood loss and at times its more than one unit of Blood Here as a replacement therapy & for maintaining Oxygen levels & some times in Moderate to severe Blood loss Massive Blood Transfusions may be required to save the Patients.
Pregnant Ladies during delivery, Caesarian section & Post Partum can be major Blood loss threatening life. Occasionally atony of Uterus can lead to severe Blood loss and needs urgent Blood Transfusion as Life saving treatment.
Any Road Accident or accident leading to Blood Loss.
Accident with Blood loss of 2 Units of Blood & or Hemoglobin less than 10 gms with reducing Hb, Abnormal Vital signs and moderate to severe injury will need Emergency Blood Transfusion as the Life Saving requirement.
Exchange Transfusion: Whole Blood / PCV along with Plasma is used for exchange transfusion in New Born Babies in Haemolytic Disease due to Rh incompatibility.
In Major Operations like Organ Transplant / Cardiac Surgery.
Platelets:Use as Life Saver.
Clinical conditions with platelet count at warning level: depends upon the clinical diagnosis and concerned operative procedures.
One unit of Random Donor Platelets( 50-70 ml) increases Platelet count by 5000-6000 platelets While Single Donor Platelets ( 220-250 ml) increases platelet count by 50,000-60,000 /cmm.
Viral Fever e.g Dengue,
D.I.C. (Small Blood clots in Blood Vessels): Platelet consumption & destruction leads to low Platelet count which may lead to Bleeding.
Cancer Patients on Treatment.
Fresh Frozen Plasma: (Provides Clotting Factors )
Patients suffering from Liver Cirrhosis
Overdose of Warferin / Blood thinning medication.
Genetic abnormality lacking one or more Clotting Factors may bleed with precipitating cause and FFP is needed as Life saving treatment.
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In Some Autoimmune diseases: Auto antibodies are developed which cannot identify its own body tissue of Host: Here Plasma Exchange Therapy works as Magic treatment.
In Recent Covid -19 out Break : Plasma from Recovered Covid-19 patients is used to treat Moderate to severely ill Covid -19 Patients
Cryoprecipittate : Use.
Cryo is prepared from FFP.
Volume is 15-20 ml.
In cardiac Patients as well as in Children It is used for Coagulation Factors as with less quantity of blood Component will supply the Coagulation Factors.
This is in short Introduction of Blood Component Usage which improve the Morbidity as well as of Utmost Importance in Life Saving Emergency Conditions.
This is Kind Appeal to Eligible Donors to come forward; save 3-4 Persons Life & Be a Hero as Life Saver Legend.
